Case Series/Study
The patient is a 36 3/7 week gestation late premature infant born with a large gastroschisis. At birth patient’s intestines were placed in a silo bag and incrementally reduced to the abdomen by nine days of life. Visceral evisceration occurs three days post repair requiring a second reduction. The hospital course was complicated by respiratory failure, anasarca, and acute kidney injury. At 20 days of life, the patient underwent gastroschisis repair with a BioMesh placement and partial skin closure. The reduction site was managed by pediatric surgery using daily betadine gauze for one month, but granulation of BioMesh to skin failed to occur. A wound care regimen utilizing Stimulen * powder x 7 weeks; Hydrofera Blue Ready* dressing x 11 weeks and later Xeroform * x 2 weeks was used as an adjunct to the BioMesh to reduce and heal the defect. Wound care was provided every 3-5 days.
Results:
One month after BioMesh grafting, reduction and closure through secondary intention were stalled. The wound care regimen described above was a successful adjunct in the reduction and closure of this large gastroschisis by secondary intention four months after installation.
Discussion:
Large gastroschisis may be closed using prosthetic material, for example, surgisis *, gore-tex*, silastic silo *, and autologous materials – umbilical cord, dura, musculocutaneous flaps, and meshed skin grafts. This case study showed that a wound care regimen can be a good adjunct and sometimes essential in these cases.
Trademarked Items: Stimulen Powder
Hydrofera Blue Ready
Xeroform Gauze
Surgisis mesh
Gore-Tex mesh
Silastic Silo bag
References: Adikibi, B. T. & O’Toole, S. (2014). Reverse tissue expansion in gastroschisis: what to do if the defect is too large to close after silo removal? Journal of Neonatal Surgery, 3(4), 47 – 49.
Bhat, V., Moront, M. & Bhandari, V. (2020). Gastroschisis: a state-of-the-art review. Children, 7, 302. doi: 10.3390/children7120302.
Ferreira, R. G., Mendonca, C. R., Ramos, L. L., de Abreu, T., do Amaral, W. N. & Ruano, R.
(2022). Gastroschisis: a systematic review of diagnosis, prognosis, and treatment. The Journal of Maternal-Fetal and Neonatal Medicine, 35(25), 6199 – 6212. doi: 10.1080/14767058.2021.1909563
Maawali, A. A. & Skarsgard, E. D. (2021). The medical and surgical management of gastroschisis. Journal of Early Human Development. Elsevier: doi.org/10.1016/j.earlhumdev.2021.105459