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Laboratory Research
A non-woven dressing composed of carboxymethylcellulose (CMC) fibres and Polyhexamethylene Biguanide (PHMB) has demonstrated broad spectrum antimicrobial efficacy across a range of timepoints from 30 minutes to 21 days. As this product can be used with a secondary cover dressing, it is important to verify that the antimicrobial performance is not compromised.
In addition, the dressings absorbency capabilities were further investigated by examining the ability of the device to absorb and retain exudate at varying viscosities to account for wound slough.
Methods:
Antimicrobial Efficacy Testing:
The antimicrobial properties of the dressing were assessed in accordance with AATCC TM -100 guidelines, incorporating parameters to simulate a secondary dressing effect. The assessment was performed against clinically relevant wound microorganisms over a period of 168hrs.
Slough Absorbency Testing:
The absorption and retention of thick wound exudate was performed in accordance with BS EN13726-1:2002. A simulated thick wound exudate (slough) was prepared and the viscosity of the solution was measured, to ensure the solution constituted a ‘thick wound exudate’ consistency. Absorbency and retention testing was performed using the slough solution.
Results:
Antimicrobial Efficacy Testing:
The data successfully demonstrates the antimicrobial performance of the PHMB dressing is not compromised by the additional secondary element, over a 168hr challenge period.
Slough Absorbency Testing:
The non-woven PHMB dressing was able to absorb a high level of slough solution when compared to a Silver non-woven dressing, and a greater amount than of a lower viscosity solution. Furthermore, the dressing was able to retain a significant level of slough solution when tested under load.
Discussion:
The in-vitro testing performed successfully verified that the antimicrobial efficacy of the non-woven PHMB dressing was not compromised when tested under simulated secondary dressing conditions, therefore providing evidence that the product remains effective.
The dressings’ ability to absorb and retain thick slough wound exudate is an added benefit in supporting the wound healing process.
Trademarked Items:
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